EA Patras secured the third spot in the league ahead of champions Iraklis on Thursday as the regular season came to an end.
The Patras side defeated Milon 3-1 at Nea Smyrni although the hosts needed a win badly to boost their chances of staying up.
Iraklis dismissed another struggling team, Apollon Kalamarias 3-0 away but will have to make do with the fourth spot in the table that will likely pit them with Panathinaikos.
The league leaders defeated Lamia 3-0 away, while second-placed Olympiakos beat visiting PAOK 3-0.
Phinikas Syrou downed relegated Ethnikos Alexandroupolis 3-1 at home and secured the sixth spot at the table, overcoming Lamia. Aris finished fifth, seeing off Kifissia 3-0 in Thessaloniki.