The reigning champions have a major task ahead of them as they face Aris in a bid to finally break into the top three on the ladder.
Olympiacos battles the Thessaloniki side at “Georgios Karaiskakis” Stadium on Monday morning (AEDT) in the premier fixture of the Greek Super League’s 18th round.
The Piraeus club is hoping to finally ascend past PAOK on the ladder, who are currently ahead of them due to a superior head-to-head record, though Aris will not make it easy for them.
Panathinaikos travels away to Giannina in what looms as a must-win match after they suffered their first loss of the season last weekend in the Athens derby.
The league leaders cannot afford to drop points again, with the eight-point lead they had at the halfway mark of the regular season now reduced to four, putting their premiership dreams in jeopardy.
AEK, the team that defeated the “Trifylli”, is looking to down Panetolikos at “Agia Sophia” ground and potentially get even closer to the Greens on the ladder.
Asteras Tripolis hosts Levadiakos and both teams will be keen on a win after some rather inconsistent campaigns thus far.
PAOK takes on OFI at “Toumba” Stadium on Sunday morning with the goal of extending their nine-match unbeaten run and keeping ahead of Olympiacos.
Lamia plays Atromitos at “Athanasios Diakos” ground in the round opener as the Fthiotida team hopes to overturn their wretched form, having earned just one point in their last five outings and gone without a victory in their past 12.
Volos goes away to challenge bottom-placed Ionikos on Tuesday morning in what looms as a perfect opportunity for the Magnesia outfit to snap their five-game winless streak.
Greek Super League Round 18 fixtures (AEDT)
Lamia-Atromitos: 02.00, Sun 15 Jan
PAOK-OFI: 05.00, Sun 15 Jan
AEK-Panetolikos: 01.00, Mon 16 Jan
Asteras Tripolis-Levadiakos: 02.00, Mon 16 Jan
Olympiacos-Aris: 04.30, Mon 16 Jan
Giannina-Panathinaikos: 05.30, Mon 16 Jan
Ionikos-Volos: 04.30, Tue 17 Jan
